401(k) · DOL Form 5500 · 2022

Vertex Pharmaceuticals Incorporated 401(k) Plan

Data updated 2026-08-11

$828M
Total assets
2,911
Participants
99th
Percentile by assets
$284,401
Avg per participant
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Official DOL plan name: Vertex Pharmaceuticals Incorporated 401(k) Plan · Sponsored by Vertex Pharmaceuticals Incorporated · Massachusetts · Professional & Technical Services

$828M in assets, 2,911 participants

Vertex Pharmaceuticals Incorporated's Vertex Pharmaceuticals Incorporated 401(k) Plan reported $828M in total assets and 2,911 participants in its 2022 DOL Form 5500 filing, ranking in the 99th percentile by assets among filed plans. Figures are as reported by the plan sponsor to the Department of Labor, not audited or endorsed by PlainRetire.

  • 99th percentile by assets (of 139,126 plans)
  • #21,377 in Professional & Technical Services (21,562 peers)

Coverage in Massachusetts

Vertex Pharmaceuticals Incorporated 401(k) Plan covers 2,911 participants in Massachusetts, 4.4x the typical Massachusetts plan (state average ~659 per filing). Assets: $828M.

$828M
total plan assets (2022 EOY)
2,911
covered participants
99th
percentile by assets (of 139,126 plans)
$284,401
avg assets per participant

The plan reported a net loss of $97M for the year, a single-year figure driven by markets and benefit payments, not a measure of plan health.

Participants vs Massachusetts filers

In Massachusetts, the average filing covers about 659 participants across 4,265 plans. Vertex Pharmaceuticals Incorporated 401(k) Plan reports 2,911 participants - 4.4x that state average ($828M EOY assets).

Massachusetts filing particulars

Total Assets (Beginning of Year)$925M
Net Assets (End of Year)$828M
Net Income-$97M
Employer EIN043039129
Plan Effective Date1990-02-01
Filing StatusFILING RECEIVED

Sponsor Plan History (Vertex Pharmaceuticals Incorporated)

$0.6B$0.8B$1B$1.2B$1.4B 202220232024 $0.83B $1.31B ▲ +57.8%
Total plan assets by year, all Vertex Pharmaceuticals Incorporated plans on file
Year Plans Participants Total Assets
2022 1 2,911 $828M
2023 1 3,789 $1.1B
2024 1 4,388 $1.3B

Nearby 401(k) Plans in Massachusetts

Peer 401(k) plans, same state, same plan type, ranked by total assets.

Vertex Pharmaceuticals Incorporated 401(k) Plan vs. nearby 401(k) plans in Massachusetts, assets vs. participants

Vertex Pharmaceuticals Incorporated 401(k) Plan vs. nearby 401(k) plans in Massachusetts, assets vs. participants Scatter plot of 6 data points. 0200004000060000 -50510152025 Total assets ($B) Participants Vertex Pharmaceutica…Fidelity Retirement …Liberty Mutual 401(k…Massachusetts Instit…Philips North Americ…Boston Scientific Co…
Vertex Pharmaceuticals Incorporated 401(k) Plan vs. nearby 401(k) plans in Massachusetts, assets vs. participants

Similar-Sized 401(k) Plans Nationally

401(k) plans in other states closest to Vertex Pharmaceuticals Incorporated 401(k) Plan by total assets, not by location.

Frequently Asked Questions

How did Vertex Pharmaceuticals Incorporated 401(k) Plan assets move in 2022?
Vertex Pharmaceuticals Incorporated 401(k) Plan pulled back noticeably - down 10.5% during 2022, from $925M to $828M. Reported net income was -$97M.
How have Vertex Pharmaceuticals Incorporated plan assets changed over time?
Across 3 plan years on file (2022-2024), Vertex Pharmaceuticals Incorporated's sponsor-wide assets grew 58.5%, from $828M to $1.3B.
Where does Vertex Pharmaceuticals Incorporated 401(k) Plan rank by assets among Form 5500 filers?
Vertex Pharmaceuticals Incorporated 401(k) Plan ranks in the 99th percentile by end-of-year assets among 139,126 plans that reported assets for plan year 2022 (among the largest 1% of all filed plans).
Which 401(k) plans are similar in size to Vertex Pharmaceuticals Incorporated 401(k) Plan?
Among 401(k) plans in other states, the closest by assets is Citrix Systems, Inc. 401(k) Plan in FL ($827M, 4,139 participants).

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Filing takeaways

Ways to act on Vertex Pharmaceuticals Incorporated 401(k) Plan's numbers.