401(k) · DOL Form 5500 · 2023

Karyopharm Therapeutics Inc. 401(k) Plan

Data updated 2026-08-25

$46M
Total assets Below avg plan size
401
Participants Below avg headcount
85th
Percentile by assets National rank
$114,844
Avg per participant Below avg balance/head
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Official DOL plan name: Karyopharm Therapeutics Inc. 401(k) Plan · Sponsored by Karyopharm Therapeutics Inc. · Massachusetts · Manufacturing

$46M in assets, 401 participants

Karyopharm Therapeutics Inc.'s Karyopharm Therapeutics Inc. 401(k) Plan reported $46M in total assets and 401 participants in its 2023 DOL Form 5500 filing, ranking in the 85th percentile by assets among filed plans. Figures are as reported by the plan sponsor to the Department of Labor, not audited or endorsed by PlainRetire.

  • #14,597 in Manufacturing (18,722 peers)

Where Karyopharm Therapeutics Inc. 401(k) Plan sits by assets

Karyopharm Therapeutics Inc. 401(k) Plan sits in the top quartile of all filed plans by assets, $46M for 401 participants (~$114,844/participant), up 27.8% in 2023.

#14,597
in Manufacturing (18,722 peers)
+27.8%
assets growth YoY
0.5×
vs typical plan assets (national mean)

Karyopharm Therapeutics Inc. 401(k) Plan's outsized position by total assets

Karyopharm Therapeutics Inc. 401(k) Plan vs every filed plan by assets

End-of-year total assets · plan year 2023 · DOL Form 5500

$46,052,253 Top 15% higher than 85% of 127,068 filed plans

This plan $0 $2,050,000,000 every filed plan with reported assets, bucketed by value

Dashed line + filled bar = this entry, among filed plans.

Source U.S. Department of Labor Form 5500 filings (EBSA) · plan year 2023

Karyopharm Therapeutics Inc. 401(k) Plan among mid-size filed plans by headcount

Plan-year 2023 Form 5500 filings with a reported participant count, partitioned by headcount band, not by assets. Karyopharm Therapeutics Inc. 401(k) Plan sits mid-pack in the medium band (401 participants).

What changed between DOL Form 5500 filings

plan year 2022 → plan year 2023

  • Karyopharm Therapeutics Inc. 401(k) Plan reported net income rose from -$3M in the plan year 2022 filing to $10M in the plan year 2023 filing.
  • Karyopharm Therapeutics Inc. 401(k) Plan end-of-year assets rose from $36M in the plan year 2022 filing to $46M in the plan year 2023 filing.

See the national 2022→2023 release diff →

EBSA filing schedule strip

Filing strip 263931704 · Karyopharm Therapeutics Inc. PY 2023 · 401(k)

Karyopharm Therapeutics Inc. 401(k) Plan · $46M · 401 · 85th

  • EIN $46M
  • EIN 401
  • EIN 85th
  • EIN 401(k)
  • EIN near Trinity Solar, LLC 401(k) Plan
  • EIN ind #14597

Stamps derive from this plan's Form 5500 line items (assets, participants, type, EIN, cohort placement) - not a quality rating of the sponsor. Read with Manufacturing retirement plans → · Plans in Massachusetts →

Karyopharm Therapeutics Inc. 401(k) Plan in the asset neighbourhood

Dexia Credit Local, New York Branch 401(k) PlanDexia Credit Local, New York…$46MSpokane Eye Clinic, Ps and Inland Empire Optical Employees 401(k) Profit Sharing PlanSpokane Eye Clinic, Ps and I…$46MKaryopharm Therapeutics Inc. 401(k) PlanKaryopharm Therapeutics Inc.…$46MTrinity Solar, LLC 401(k) PlanTrinity Solar, LLC 401(k) Pl…$46MZara USA & Related Companies 401(k) PlanZara USA & Related Companies…$46M
End-of-year total assets ($M) among Karyopharm Therapeutics Inc. 401(k) Plan and nearest nationwide 401(k) peers. Source: DOL Form 5500 plan year 2023.

Scale-class filing particulars (2023)

Total Assets (Beginning of Year)$36M
Net Assets (End of Year)$46M
Net Income$10M
Employer EIN263931704
Plan Effective Date2011-01-01
Filing StatusFILING RECEIVED

Sponsor Plan History (Karyopharm Therapeutics Inc.)

Sponsor-wide plan assets over time

All Karyopharm Therapeutics Inc. plans reported in each filing year

Latest sponsor-wide plan assets
$56M 54.337162503724755% vs 2022
2024 filing year
$30M$40M$50M$60M 202220232024 $36M $55.6M ▲ +54.4%
Year Plans Participants Total Assets
2022 1 405 $36M
2023 1 401 $46M
2024 1 308 $56M

Nearby 401(k) Plans in Massachusetts

Peer 401(k) plans, same state, same plan type, ranked by total assets.

Karyopharm Therapeutics Inc. 401(k) Plan vs. nearby 401(k) plans in Massachusetts, assets vs. participants Scatter plot of 6 data points. -20000020000400006000080000 -10010203040 Total assets ($B) Participants Karyopharm Therapeutics Inc. 401(k) Plan, Total assets ($B): 0.046052253 · Participants: 401Karyopharm Therapeutics Inc. 401(k) PlanFidelity Retirement Savings Plan, Total assets ($B): 28.649852331 · Participants: 62289Fidelity Retirement Savings PlanLiberty Mutual 401(k) Plan, Total assets ($B): 10.556596852 · Participants: 37052Liberty Mutual 401(k) PlanMassachusetts Institute of Technology Supplemental 401(k) Plan, Total assets ($B): 6.829912863 · Participants: 14094Massachusetts Institute of Technology Supplemental 401(k) PlanBoston Scientific Corporation 401(k) Retirement Savings Plan, Total assets ($B): 5.786107181 · Participants: 19881Boston Scientific Corporation 401(k) Retirement Savings PlanPhilips North America 401(k) Plan, Total assets ($B): 5.779286156 · Participants: 19120Philips North America 401(k) Plan
Karyopharm Therapeutics Inc. 401(k) Plan vs. nearby 401(k) plans in Massachusetts, assets vs. participants
Compare Karyopharm Therapeutics Inc. 401(k) Plan side-by-side with 3 peers →

Karyopharm Therapeutics Inc. 401(k) Plan's out-of-state 401(k) peers by assets and headcount

Outside Massachusetts, the nearest 401(k) by assets is Trinity Solar, LLC 401(k) Plan in NJ ($46M); by covered participants it is Aquafil USA, Inc. 401(k) Plan in GA (401 participants). Same-state nearby plans are listed separately above.

Similar participant headcount

Nearest other-state filings by covered participants (401 participants); asset peers above are excluded.

DOL Form 5500 plan year 2023. Asset totals can differ widely at the same headcount; neither axis is a quality rating.

Frequently Asked Questions

How did Karyopharm Therapeutics Inc. 401(k) Plan assets move in 2023? ▼
Karyopharm Therapeutics Inc. 401(k) Plan grew sharply - up 27.8% during 2023, from $36M to $46M. Reported net income was $10M.
How have Karyopharm Therapeutics Inc. plan assets changed over time? ▼
Across 3 plan years on file (2022-2024), Karyopharm Therapeutics Inc.'s sponsor-wide assets grew 54.3%, from $36M to $56M.
Where does Karyopharm Therapeutics Inc. 401(k) Plan rank by assets among Form 5500 filers? ▼
Karyopharm Therapeutics Inc. 401(k) Plan ranks in the 85th percentile by end-of-year assets among 127,072 plans that reported assets for plan year 2023 (in the top quartile of all filed plans by assets).
Which 401(k) plans are similar in size to Karyopharm Therapeutics Inc. 401(k) Plan? ▼
Among 401(k) plans in other states, the closest by assets is Trinity Solar, LLC 401(k) Plan in NJ ($46M, 1,911 participants).
Which 401(k) plans cover a similar participant headcount to Karyopharm Therapeutics Inc. 401(k) Plan? ▼
Among 401(k) plans in other states, the closest by covered participants is Aquafil USA, Inc. 401(k) Plan in GA (401 participants, $5M in assets).

Source: U.S. Department of Labor, Employee Benefits Security Administration (EBSA), Form 5500 public disclosure dataset. Plan year 2023.

Source: DOL EFAST2 filing system (efast.dol.gov) - original filing retrieval by EIN 263931704.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from U.S. Department of Labor Form 5500 filings (EBSA). See our methodology for details.