401(k) · DOL Form 5500 · 2024

2seventy Bio, Inc. 401(k) Plan

Data updated 2026-05-15

$32M
Total assets
276
Participants
78th
Percentile by assets
$117,089
Avg per participant

Sponsored by 2seventy Bio, Inc. · Massachusetts · Professional & Technical Services

What the 2024 filing shows

2seventy Bio, Inc. 401(k) Plan holds $32M for 276 participants - about $117,089 per participant, in the top quartile of all filed plans by assets, down 27.3% over the 2024 plan year.

$32M
total plan assets (2024 EOY)
276
covered participants
78th
percentile by assets (of 116,472 plans)
$117,089
avg assets per participant

The plan reported a net loss of $12M for the year, a single-year figure driven by markets and benefit payments, not a measure of plan health.

Industry
Professional & Technical Services

401(k) · DOL Form 5500 · 2024

What the Filing Says About 2seventy Bio, Inc. 401(k) Plan

2seventy Bio, Inc. 401(k) Plan is a 401(k) retirement plan sponsored by 2seventy Bio, Inc., headquartered in Massachusetts. According to the U.S. Department of Labor's 2024 Form 5500 filing, the plan reports $32M in total end-of-year assets and covers 276 participants across the Professional & Technical Services industry. The sponsor's EIN on file with the U.S. Department of Labor is 863658454, and the plan has been effective since 2021-11-01. Its filing status is currently FILING RECEIVED.

Year over year, total assets declined sharply from $44M at the beginning of 2024 to $32M at year-end - down 27.3%. Net assets (after liabilities) closed the year at $32M, with reported net income of -$12M driven by investment returns, contributions received, and benefit payments during the period. These figures reflect what the plan administrator certified on Schedule H or Schedule I of the Form 5500 annual return and can be compared against 2 prior plan-year filings from the same sponsor shown below.

Across the 3 plan years 2seventy Bio, Inc. has on file with PlainRetire (2022-2024), sponsor-wide plan assets have moved from $30M to $32M, a gain of 6.7%, while reported participants moved from 416 to 276 (-33.7%). The strongest year on file by total sponsor assets was 2023 at $44M; the softest was 2022 at $30M. Year-by-year, sponsor-wide filings show: 2022 - $30M in assets across 1 plan covering 416 participants; 2023 - $44M in assets across 1 plan covering 413 participants; 2024 - $32M in assets across 1 plan covering 276 participants.

By assets, 2seventy Bio, Inc. 401(k) Plan outranks 78% of the 116,472 plans that filed a Form 5500 for the 2024 plan year, and holds roughly 0.3x the national average plan size of $100M and 730 average participants.

Asset totals and participant counts reflect a single plan year snapshot and can change materially with market conditions, plan mergers, or workforce changes. Fields such as "net income" include both realized investment performance and contribution/distribution flows, a single-year figure does not by itself indicate plan health or participant outcomes. This page summarizes public DOL disclosures for research and educational purposes only and is not retirement, tax, legal, or financial advice. Before making decisions about your own retirement benefits or evaluating an employer's plan, verify the underlying filing directly via the DOL EFAST2 system and consult a qualified professional.

How the percentile is calculated: we count every plan that filed a 2024 Form 5500 with a reported end-of-year asset figure (116,472 plans), rank 2seventy Bio, Inc. 401(k) Plan against all of them by total assets, and report the share of those plans it outranks. A plan reporting no asset figure for the year is excluded from the ranking rather than assumed to be zero.

Financial Summary (2024)

Total Assets (Beginning of Year)$44M
Total Assets (End of Year)$32M
Net Assets (End of Year)$32M
Net Income-$12M
Plan Type401(k)
Employer EIN863658454
Plan Effective Date2021-11-01
Filing StatusFILING RECEIVED

Sponsor Plan History (2seventy Bio, Inc.)

Year Plans Participants Total Assets
2022 1 416 $30M
2023 1 413 $44M
2024 1 276 $32M

Nearby 401(k) Plans in Massachusetts

Peer 401(k) plans, same state, same plan type, ranked by total assets.

Frequently Asked Questions

How much money is in the 2seventy Bio, Inc. 401(k) Plan?
As of the 2024 Form 5500 filing, 2seventy Bio, Inc. 401(k) Plan holds $32M in total assets with 276 participants. It is sponsored by 2seventy Bio, Inc..
What type of plan is 2seventy Bio, Inc. 401(k) Plan?
2seventy Bio, Inc. 401(k) Plan is a 401(k) plan. It has been effective since 2021-11-01. The plan is filed with the U.S. Department of Labor under EIN 863658454.
Who sponsors the 2seventy Bio, Inc. 401(k) Plan?
2seventy Bio, Inc. 401(k) Plan is sponsored by 2seventy Bio, Inc., located in Massachusetts. The sponsor's EIN is 863658454 and the plan operates in the Professional & Technical Services industry.
How did 2seventy Bio, Inc. 401(k) Plan perform in 2024?
2seventy Bio, Inc. 401(k) Plan declined sharply - down 27.3% during 2024, moving from $44M to $32M in total assets. Net income was -$12M.

What this filing means

Ways to act on 2seventy Bio, Inc. 401(k) Plan's numbers.

Source: U.S. Department of Labor, Employee Benefits Security Administration (EBSA), Form 5500 public disclosure dataset. Plan year 2024.

Source: DOL EFAST2 filing system (efast.dol.gov) - original filing retrieval by EIN 863658454.

Reference: IRS Publication 560, Retirement Plans for Small Business, contribution-limit rules.

Reference: IRS Publication 590-B, Distributions from IRAs, RMD rules under SECURE Act 2.0.

Data sourced from U.S. Department of Labor Form 5500 filings (EBSA). See our methodology for details.

Every figure on PlainRetire is rendered directly from the Department of Labor's Form 5500 annual return filings, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-05-15.