401(k) · DOL Form 5500 · 2024

Ionis Pharmaceuticals, Inc. 401(k) Plan

Data updated 2026-07-24

$316M
Total assets
897
Participants
96th
Percentile by assets
$352,240
Avg per participant

Official DOL plan name: Ionis Pharmaceuticals 401(k) Plan · Sponsored by Ionis Pharmaceuticals, Inc. · California · Professional & Technical Services

$316M in assets, 897 participants

Ionis Pharmaceuticals, Inc.'s Ionis Pharmaceuticals 401(k) Plan reported $316M in total assets and 897 participants in its 2024 DOL Form 5500 filing, ranking in the 96th percentile by assets among filed plans. Figures are as reported by the plan sponsor to the Department of Labor, not audited or endorsed by PlainRetire.

  • 96th percentile by assets (of 116,472 plans)

What the 2024 filing shows

Ionis Pharmaceuticals 401(k) Plan holds $316M for 897 participants - about $352,240 per participant, in the top 5% of all filed plans by assets, up 24.0% over the 2024 plan year.

$316M
total plan assets (2024 EOY)
897
covered participants
96th
percentile by assets (of 116,472 plans)
$352,240
avg assets per participant
State
Industry
Professional & Technical Services

401(k) · DOL Form 5500 · 2024

What the Filing Says About Ionis Pharmaceuticals 401(k) Plan

Ionis Pharmaceuticals 401(k) Plan is a 401(k) retirement plan sponsored by Ionis Pharmaceuticals, Inc., headquartered in California. According to the U.S. Department of Labor's 2024 Form 5500 filing, the plan reports $316M in total end-of-year assets and covers 897 participants across the Professional & Technical Services industry. The sponsor's EIN on file with the U.S. Department of Labor is 330336973, and the plan has been effective since 1991-01-01. Its filing status is currently FILING RECEIVED.

Year over year, total assets grew sharply from $255M at the beginning of 2024 to $316M at year-end - up 24.0%. Net assets (after liabilities) closed the year at $316M, with reported net income of $61M driven by investment returns, contributions received, and benefit payments during the period. These figures reflect what the plan administrator certified on Schedule H or Schedule I of the Form 5500 annual return and can be compared against 2 prior plan-year filings from the same sponsor shown below.

Across the 3 plan years Ionis Pharmaceuticals, Inc. has on file with PlainRetire (2022-2024), sponsor-wide plan assets have moved from $195M to $316M, a gain of 62.0%, while reported participants moved from 609 to 897 (+47.3%). The strongest year on file by total sponsor assets was 2024 at $316M; the softest was 2022 at $195M. Year-by-year, sponsor-wide filings show: 2022 - $195M in assets across 1 plan covering 609 participants; 2023 - $255M in assets across 1 plan covering 760 participants; 2024 - $316M in assets across 1 plan covering 897 participants.

By assets, Ionis Pharmaceuticals 401(k) Plan outranks 96% of the 116,472 plans that filed a Form 5500 for the 2024 plan year, and holds roughly 3.2x the national average plan size of $100M and 730 average participants.

Asset totals and participant counts reflect a single plan year snapshot and can change materially with market conditions, plan mergers, or workforce changes. Fields such as "net income" include both realized investment performance and contribution/distribution flows, a single-year figure does not by itself indicate plan health or participant outcomes. This page summarizes public DOL disclosures for research and educational purposes only and is not retirement, tax, legal, or financial advice. Before making decisions about your own retirement benefits or evaluating an employer's plan, verify the underlying filing directly via the DOL EFAST2 system and consult a qualified professional.

How the percentile is calculated: we count every plan that filed a 2024 Form 5500 with a reported end-of-year asset figure (116,472 plans), rank Ionis Pharmaceuticals 401(k) Plan against all of them by total assets, and report the share of those plans it outranks. A plan reporting no asset figure for the year is excluded from the ranking rather than assumed to be zero.

Financial Summary (2024)

Total Assets (Beginning of Year)$255M
Total Assets (End of Year)$316M
Net Assets (End of Year)$316M
Net Income$61M
Plan Type401(k)
Employer EIN330336973
Plan Effective Date1991-01-01
Filing StatusFILING RECEIVED

Sponsor Plan History (Ionis Pharmaceuticals, Inc.)

$150M$200M$250M$300M$350M 202220232024 $195M $316M ▲ +62.0%
Total plan assets by year, all Ionis Pharmaceuticals, Inc. 401(k) plans on file
Year Plans Participants Total Assets
2022 1 609 $195M
2023 1 760 $255M
2024 1 897 $316M

Nearby 401(k) Plans in California

Peer 401(k) plans, same state, same plan type, ranked by total assets.

Ionis Pharmaceuticals 401(k) Plan vs. nearby 401(k) plans in California, assets vs. participants

Ionis Pharmaceuticals 401(k) Plan vs. nearby 401(k) plans in California, assets vs. participants Scatter plot of 6 data points. -50000050000100000150000 -200204060 Total assets ($B) Participants Ionis Pharmaceutical…Google LLC 401(k) Sa…Oracle Corporation 4…Intel 401(k) Savings…Apple 401(k) PlanCisco Systems,Inc. 4…
Ionis Pharmaceuticals 401(k) Plan vs. nearby 401(k) plans in California, assets vs. participants

Similar-Sized 401(k) Plans Nationally

401(k) plans in other states closest to Ionis Pharmaceuticals 401(k) Plan by total assets, not by location.

Frequently Asked Questions

How much money is in the Ionis Pharmaceuticals 401(k) Plan?
As of the 2024 Form 5500 filing, Ionis Pharmaceuticals 401(k) Plan holds $316M in total assets with 897 participants. It is sponsored by Ionis Pharmaceuticals, Inc..
What type of plan is Ionis Pharmaceuticals 401(k) Plan?
Ionis Pharmaceuticals 401(k) Plan is a 401(k) plan. It has been effective since 1991-01-01. The plan is filed with the U.S. Department of Labor under EIN 330336973.
Who sponsors the Ionis Pharmaceuticals 401(k) Plan?
Ionis Pharmaceuticals 401(k) Plan is sponsored by Ionis Pharmaceuticals, Inc., located in California. The sponsor's EIN is 330336973 and the plan operates in the Professional & Technical Services industry.
How did Ionis Pharmaceuticals 401(k) Plan perform in 2024?
Ionis Pharmaceuticals 401(k) Plan grew sharply - up 24.0% during 2024, moving from $255M to $316M in total assets. Net income was $61M.

What this filing means

Ways to act on Ionis Pharmaceuticals 401(k) Plan's numbers.

Source: U.S. Department of Labor, Employee Benefits Security Administration (EBSA), Form 5500 public disclosure dataset. Plan year 2024.

Source: DOL EFAST2 filing system (efast.dol.gov) - original filing retrieval by EIN 330336973.

Reference: IRS Publication 560, Retirement Plans for Small Business, contribution-limit rules.

Reference: IRS Publication 590-B, Distributions from IRAs, RMD rules under SECURE Act 2.0.

Data sourced from U.S. Department of Labor Form 5500 filings (EBSA). See our methodology for details.

Every figure on PlainRetire is rendered directly from the Department of Labor's Form 5500 annual return filings, no number is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-07-24.