401(k) · DOL Form 5500 · 2022

Ionis Pharmaceuticals, Inc. 401(k) Plan

Data updated 2026-08-25

$195M
Total assets Near avg plan size
609
Participants Below avg headcount
96th
Percentile by assets National rank
$320,283
Avg per participant High balance/head
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Official DOL plan name: Ionis Pharmaceuticals 401(k) Plan · Sponsored by Ionis Pharmaceuticals, Inc. · California · Professional & Technical Services

$195M in assets, 609 participants

Ionis Pharmaceuticals, Inc.'s Ionis Pharmaceuticals 401(k) Plan reported $195M in total assets and 609 participants in its 2022 DOL Form 5500 filing, ranking in the 96th percentile by assets among filed plans. Figures are as reported by the plan sponsor to the Department of Labor, not audited or endorsed by PlainRetire.

  • #20,828 in Professional & Technical Services (21,562 peers)

Where Ionis Pharmaceuticals 401(k) Plan sits by assets

Ionis Pharmaceuticals 401(k) Plan sits in the top 5% of all filed plans by assets, $195M for 609 participants (~$320,283/participant), down 16.8% in 2022.

#20,828
in Professional & Technical Services (21,562 peers)
-16.8%
assets change YoY
2.0×
vs typical plan assets (national mean)

The plan reported a net loss of $39M for the year, a single-year figure driven by markets and benefit payments, not a measure of plan health.

Ionis Pharmaceuticals 401(k) Plan's outsized position by total assets

Ionis Pharmaceuticals 401(k) Plan vs every filed plan by assets

End-of-year total assets · plan year 2022 · DOL Form 5500

$195,052,138 Top 4% higher than 96% of 139,123 filed plans

This plan $0 $2,050,000,000 every filed plan with reported assets, bucketed by value

Dashed line + filled bar = this entry, among filed plans.

Source U.S. Department of Labor Form 5500 filings (EBSA) · plan year 2022

Ionis Pharmaceuticals 401(k) Plan among mid-size filed plans by headcount

Plan-year 2022 Form 5500 filings with a reported participant count, partitioned by headcount band, not by assets. Ionis Pharmaceuticals 401(k) Plan sits mid-pack in the medium band (609 participants).

Form 5500 schedule snapshot

Filing strip 330336973 · Ionis Pharmaceuticals, Inc. PY 2022 · 401(k)

Ionis Pharmaceuticals 401(k) Plan · $195M · 609 · 96th

  • EIN $195M
  • RANK 609
  • PHOTO 96th
  • IND 401(k)
  • EOY near Bluestem 401(k) Retirement Savings Plan
  • 5500 ind #20828

Stamps derive from this plan's Form 5500 line items (assets, participants, type, EIN, cohort placement) - not a quality rating of the sponsor. Read with Professional & Technical Services retirement plans → · Plans in California →

Ionis Pharmaceuticals 401(k) Plan in the asset neighbourhood

Afscme Employees Salary Savings PlanAfscme Employees Salary Savi…$195MMitel 401(k) Plan$195MIonis Pharmaceuticals 401(k) PlanIonis Pharmaceuticals 401(k)…$195MBluestem 401(k) Retirement Savings PlanBluestem 401(k) Retirement S…$195MWieden & Kennedy, Inc. 401(k) Profit Sharing PlanWieden & Kennedy, Inc. 401(k…$195M
End-of-year total assets ($M) among Ionis Pharmaceuticals 401(k) Plan and nearest nationwide 401(k) peers. Source: DOL Form 5500 plan year 2022.

Scale-class filing particulars (2022)

Total Assets (Beginning of Year)$235M
Net Assets (End of Year)$195M
Net Income-$39M
Employer EIN330336973
Plan Effective Date1991-01-01
Filing StatusFILING RECEIVED

Sponsor Plan History (Ionis Pharmaceuticals, Inc.)

Sponsor-wide plan assets over time

All Ionis Pharmaceuticals, Inc. plans reported in each filing year

Latest sponsor-wide plan assets
$316M 61.98715340408112% vs 2022
2024 filing year
$150M$200M$250M$300M$350M 202220232024 $195M $316M ▲ +62.0%
Year Plans Participants Total Assets
2022 1 609 $195M
2023 1 760 $255M
2024 1 897 $316M

Nearby 401(k) Plans in California

Peer 401(k) plans, same state, same plan type, ranked by total assets.

Ionis Pharmaceuticals 401(k) Plan vs. nearby 401(k) plans in California, assets vs. participants Scatter plot of 6 data points. -50000050000100000150000200000250000 -200204060 Total assets ($B) Participants Ionis Pharmaceuticals 401(k) Plan, Total assets ($B): 0.195052138 · Participants: 609Ionis Pharmaceuticals 401(k) PlanWells Fargo & Company 401(k) Plan, Total assets ($B): 45.765616608 · Participants: 205865Wells Fargo & Company 401(k) PlanGoogle LLC 401(k) Savings Plan, Total assets ($B): 28.89820221 · Participants: 102963Google LLC 401(k) Savings PlanOracle Corporation 401(k) Savings and Investment Plan, Total assets ($B): 21.851716605 · Participants: 46320Oracle Corporation 401(k) Savings and Investment PlanChevron Employee Savings Investment Plan, Total assets ($B): 18.60989746 · Participants: 19946Chevron Employee Savings Investment PlanIntel 401(k) Savings Plan, Total assets ($B): 18.361585903 · Participants: 54672Intel 401(k) Savings Plan
Ionis Pharmaceuticals 401(k) Plan vs. nearby 401(k) plans in California, assets vs. participants
Compare Ionis Pharmaceuticals 401(k) Plan side-by-side with 3 peers →

Ionis Pharmaceuticals 401(k) Plan's out-of-state 401(k) peers by assets and headcount

Outside California, the nearest 401(k) by assets is Bluestem 401(k) Retirement Savings Plan in MN ($195M); by covered participants it is Plymouth Tube Company 401(k) Savings Plan and Trust in IL (609 participants). Same-state nearby plans are listed separately above.

Closest by plan assets

Nearest other-state filings by tot_assets_eoy ($195M here).

Similar participant headcount

Nearest other-state filings by covered participants (609 participants); asset peers above are excluded.

DOL Form 5500 plan year 2022. Asset totals can differ widely at the same headcount; neither axis is a quality rating.

Frequently Asked Questions

How did Ionis Pharmaceuticals 401(k) Plan assets move in 2022? ▼
Ionis Pharmaceuticals 401(k) Plan declined sharply - down 16.8% during 2022, from $235M to $195M. Reported net income was -$39M.
How have Ionis Pharmaceuticals, Inc. plan assets changed over time? ▼
Across 3 plan years on file (2022-2024), Ionis Pharmaceuticals, Inc.'s sponsor-wide assets grew 62.0%, from $195M to $316M.
Where does Ionis Pharmaceuticals 401(k) Plan rank by assets among Form 5500 filers? ▼
Ionis Pharmaceuticals 401(k) Plan ranks in the 96th percentile by end-of-year assets among 139,126 plans that reported assets for plan year 2022 (in the top 5% of all filed plans by assets).
Which 401(k) plans are similar in size to Ionis Pharmaceuticals 401(k) Plan? ▼
Among 401(k) plans in other states, the closest by assets is Bluestem 401(k) Retirement Savings Plan in MN ($195M, 1,626 participants).
Which 401(k) plans cover a similar participant headcount to Ionis Pharmaceuticals 401(k) Plan? ▼
Among 401(k) plans in other states, the closest by covered participants is Plymouth Tube Company 401(k) Savings Plan and Trust in IL (609 participants, N/A in assets).

Source: U.S. Department of Labor, Employee Benefits Security Administration (EBSA), Form 5500 public disclosure dataset. Plan year 2022.

Source: DOL EFAST2 filing system (efast.dol.gov) - original filing retrieval by EIN 330336973.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from U.S. Department of Labor Form 5500 filings (EBSA). See our methodology for details.