401(k) · DOL Form 5500 · 2023

Ionis Pharmaceuticals, Inc. 401(k) Plan

Data updated 2026-08-25

$255M
Total assets Near avg plan size
760
Participants Near avg headcount
96th
Percentile by assets National rank
$335,278
Avg per participant High balance/head
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Official DOL plan name: Ionis Pharmaceuticals 401(k) Plan · Sponsored by Ionis Pharmaceuticals, Inc. · California · Professional & Technical Services

$255M in assets, 760 participants

Ionis Pharmaceuticals, Inc.'s Ionis Pharmaceuticals 401(k) Plan reported $255M in total assets and 760 participants in its 2023 DOL Form 5500 filing, ranking in the 96th percentile by assets among filed plans. Figures are as reported by the plan sponsor to the Department of Labor, not audited or endorsed by PlainRetire.

  • #19,661 in Professional & Technical Services (20,321 peers)

Where Ionis Pharmaceuticals 401(k) Plan sits by assets

Ionis Pharmaceuticals 401(k) Plan sits in the top 5% of all filed plans by assets, $255M for 760 participants (~$335,278/participant), up 30.6% in 2023.

#19,661
in Professional & Technical Services (20,321 peers)
+30.6%
assets growth YoY
2.6×
vs typical plan assets (national mean)

Ionis Pharmaceuticals 401(k) Plan's outsized position by total assets

Ionis Pharmaceuticals 401(k) Plan vs every filed plan by assets

End-of-year total assets · plan year 2023 · DOL Form 5500

$254,811,590 Top 4% higher than 96% of 127,068 filed plans

This plan $0 $2,050,000,000 every filed plan with reported assets, bucketed by value

Dashed line + filled bar = this entry, among filed plans.

Source U.S. Department of Labor Form 5500 filings (EBSA) · plan year 2023

Ionis Pharmaceuticals 401(k) Plan among mid-size filed plans by headcount

Plan-year 2023 Form 5500 filings with a reported participant count, partitioned by headcount band, not by assets. Ionis Pharmaceuticals 401(k) Plan sits mid-pack in the medium band (760 participants).

What changed between DOL Form 5500 filings

plan year 2022 → plan year 2023

  • Ionis Pharmaceuticals 401(k) Plan reported net income rose from -$39M in the plan year 2022 filing to $60M in the plan year 2023 filing.
  • Ionis Pharmaceuticals 401(k) Plan end-of-year assets rose from $195M in the plan year 2022 filing to $255M in the plan year 2023 filing.
  • Ionis Pharmaceuticals 401(k) Plan reported participants rose from 609 in the plan year 2022 filing to 760 in the plan year 2023 filing.

See the national 2022→2023 release diff →

DOL schedule card

Filing strip 330336973 · Ionis Pharmaceuticals, Inc. PY 2023 · 401(k)

Ionis Pharmaceuticals 401(k) Plan · $255M · 760 · 96th

  • 5500 $255M
  • 5500 760
  • 5500 96th
  • 5500 401(k)
  • 5500 near Software Ag USA, Inc. Profit Sharing Plan
  • 5500 ind #19661

Stamps derive from this plan's Form 5500 line items (assets, participants, type, EIN, cohort placement) - not a quality rating of the sponsor. Read with Professional & Technical Services retirement plans → · Plans in California →

Ionis Pharmaceuticals 401(k) Plan in the asset neighbourhood

Capital Accumulation Plan$255MIonis Pharmaceuticals 401(k) PlanIonis Pharmaceuticals 401(k)…$255MSoftware Ag USA, Inc. Profit Sharing PlanSoftware Ag USA, Inc. Profit…$255MMitsubishi Motors North America, Inc. 401(k) Savings PlanMitsubishi Motors North Amer…$255MUnited Community Banks, Inc. 401(k) PlanUnited Community Banks, Inc.…$255M
End-of-year total assets ($M) among Ionis Pharmaceuticals 401(k) Plan and nearest nationwide 401(k) peers. Source: DOL Form 5500 plan year 2023.

Scale-class filing particulars (2023)

Total Assets (Beginning of Year)$195M
Net Assets (End of Year)$255M
Net Income$60M
Employer EIN330336973
Plan Effective Date1991-01-01
Filing StatusFILING RECEIVED

Sponsor Plan History (Ionis Pharmaceuticals, Inc.)

Sponsor-wide plan assets over time

All Ionis Pharmaceuticals, Inc. plans reported in each filing year

Latest sponsor-wide plan assets
$316M 61.98715340408112% vs 2022
2024 filing year
$150M$200M$250M$300M$350M 202220232024 $195M $316M ▲ +62.0%
Year Plans Participants Total Assets
2022 1 609 $195M
2023 1 760 $255M
2024 1 897 $316M

Nearby 401(k) Plans in California

Peer 401(k) plans, same state, same plan type, ranked by total assets.

Ionis Pharmaceuticals 401(k) Plan vs. nearby 401(k) plans in California, assets vs. participants Scatter plot of 6 data points. -50000050000100000150000200000250000 -200204060 Total assets ($B) Participants Ionis Pharmaceuticals 401(k) Plan, Total assets ($B): 0.25481159 · Participants: 760Ionis Pharmaceuticals 401(k) PlanWells Fargo & Company 401(k) Plan, Total assets ($B): 51.831350351 · Participants: 193919Wells Fargo & Company 401(k) PlanGoogle LLC 401(k) Savings Plan, Total assets ($B): 39.047152408 · Participants: 122867Google LLC 401(k) Savings PlanOracle Corporation 401(k) Savings and Investment Plan, Total assets ($B): 26.320437734 · Participants: 63105Oracle Corporation 401(k) Savings and Investment PlanIntel 401(k) Savings Plan, Total assets ($B): 22.17918189 · Participants: 59863Intel 401(k) Savings PlanApple 401(k) Plan, Total assets ($B): 19.779511539 · Participants: 106111Apple 401(k) Plan
Ionis Pharmaceuticals 401(k) Plan vs. nearby 401(k) plans in California, assets vs. participants
Compare Ionis Pharmaceuticals 401(k) Plan side-by-side with 3 peers →

Ionis Pharmaceuticals 401(k) Plan's out-of-state 401(k) peers by assets and headcount

Outside California, the nearest 401(k) by assets is Software Ag USA, Inc. Profit Sharing Plan in VA ($255M); by covered participants it is Clarins USA, Inc. 401(k) Plan in NY (760 participants). Same-state nearby plans are listed separately above.

Closest by plan assets

Nearest other-state filings by tot_assets_eoy ($255M here).

Similar participant headcount

Nearest other-state filings by covered participants (760 participants); asset peers above are excluded.

DOL Form 5500 plan year 2023. Asset totals can differ widely at the same headcount; neither axis is a quality rating.

Frequently Asked Questions

How did Ionis Pharmaceuticals 401(k) Plan assets move in 2023? ▼
Ionis Pharmaceuticals 401(k) Plan surged - up 30.6% during 2023, from $195M to $255M. Reported net income was $60M.
How have Ionis Pharmaceuticals, Inc. plan assets changed over time? ▼
Across 3 plan years on file (2022-2024), Ionis Pharmaceuticals, Inc.'s sponsor-wide assets grew 62.0%, from $195M to $316M.
Where does Ionis Pharmaceuticals 401(k) Plan rank by assets among Form 5500 filers? ▼
Ionis Pharmaceuticals 401(k) Plan ranks in the 96th percentile by end-of-year assets among 127,072 plans that reported assets for plan year 2023 (in the top 5% of all filed plans by assets).
Which 401(k) plans are similar in size to Ionis Pharmaceuticals 401(k) Plan? ▼
Among 401(k) plans in other states, the closest by assets is Software Ag USA, Inc. Profit Sharing Plan in VA ($255M, 587 participants).
Which 401(k) plans cover a similar participant headcount to Ionis Pharmaceuticals 401(k) Plan? ▼
Among 401(k) plans in other states, the closest by covered participants is Clarins USA, Inc. 401(k) Plan in NY (760 participants, $44M in assets).

Source: U.S. Department of Labor, Employee Benefits Security Administration (EBSA), Form 5500 public disclosure dataset. Plan year 2023.

Source: DOL EFAST2 filing system (efast.dol.gov) - original filing retrieval by EIN 330336973.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from U.S. Department of Labor Form 5500 filings (EBSA). See our methodology for details.